The influence on serum protein concentration of the protein intake in high-carbohydrate diets.

I. Healthy young men ate diets high in carbohydrate with a fixed protein content: (a) 18 % protein with maize starch, (b ) 18% protein with sucrose, (c) 9% protein with sucrose. Sucrose or starch was given at a level of 7 g/kg body-weight per day. 2. The serum albumin concentration fell by 7-10% after 16 days with all three diets; the falls were statistically significant. No change in y-globulin concentration was seen with the 18 yo protein diets. With the 9 % protein diet there was a significant increase in this fraction. The P-globulin concentration rose significantly with the diet containing 18 yo protein with sucrose but there was no change in this fraction with the other diets. aland c+globulins rose significantly with the diet containing 18% protein with sucrose but no increase in these fractions was seen on the other diets. 3. Possible mechanisms concerned in the production of these changes are discussed.